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The BlueM formula with active oxygen is very important in the healing process of wounds. To gain a greater understanding of BlueM's effectiveness, it is important to understand the scientific research surrounding the part oxygen plays in the wound healing process
Role active oxygen
1. Increases Cell Metabolism and Energy Production
Oxygen is required for intracellular processes like biosynthesis, movement, and transport. It needs energy to be functional, as well as for cell survival.
2. Increases Rate of Cell Proliferation and Reepithelialization
Epithelial cells “march in” from the sides to close the wound and form a barrier between the wound and the environment – this is the foundation for forming new skin.
3. Increases Collagen Synthesis and Tensile Strength
Oxygen is essential to make and properly organise collagen. This is the primary component of the skin, accounting for 70-80% (dry weight – without water) and acts as the structural scaffold of the skin. Organised collagen is bundled into fibers (like strands of rope), which are interwoven and can be stretched in multiple directions without tearing (the collagen fibers are woven similar to fabric).
4. Increases Anti-bacterial Activities
Oxygen is essential for respiratory burst. This is the production of reactive oxygen species (ROS) used by phagocytes such as neutrophils and macrophages in bactericidal activity. It also involves the removal of necrotic cellular debris.
5. Increases Angiogenesis and Promotes Revascularization
The creation of new blood vessels (angiogenesis) is essential to the growth and survival of repair tissue. Oxygen levels directly affect the rate and quality of new blood vessel growth.
6. Promotes Growth Factor Signaling Transduction
Reactive oxygen species (ROS) are essential for the signaling processes of growth factors and processes such as leukocyte recruitment, cell motility, angiogenesis and extracellular matrix formation.
Mechanisms of action of BlueM active oxygen products
In order to increase the active oxygen on a local wound area, the use of both low concentrations of sodium perborate and of enzyme glucose oxidase (GOX - found in honey) promotes a more rapid healing process. This as well as low concentrations of hydrogen peroxide are included within the unique BlueM formula. Research shows that the continued presence of a low concentration of hydrogen peroxide is a very effective to normalise and control harmfull bacteria.
Using BlueM at the point of the acute wound allows increased active oxygen to work on the chronic situation (periodontitis or peri-implantitis). Through stimulating the wound healing process. BlueM improves the overall oral health (plaque score, bleeding index) keeping the mouth healthy.
The BlueM formula is developed to provide a healthy body through effectively maintain a high level of oral care. It provides the most effective solutions for each patient.
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